Membrane cholesterol and the regulation of signal transduction.
نویسندگان
چکیده
The plasma membrane of mammalian cells consists of microdomains differing in lipid and protein composition. Two distinct classes of cholesterol/sphingolipid microdomain (caveolae and lipid rafts) are assembly points for transmembrane signalling complexes. Recent evidence suggests that transient changes in cholesterol content may be important in regulating signal transduction.
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ورودعنوان ژورنال:
- Biochemical Society transactions
دوره 32 Pt 1 شماره
صفحات -
تاریخ انتشار 2004